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5-Methyltryptamine hydrochloride
CAS No. 1010-95-3
5-Methyltryptamine hydrochloride ( 2-(5-Methyl-1H-indol-3-yl)ethanamine hydrochloride )
Catalog No. M27167 CAS No. 1010-95-3
5-Methyltryptamine hydrochloride is a high-affinity 5-HT1C receptor ligand and a partial agonist of 5-HT.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Name5-Methyltryptamine hydrochloride
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NoteResearch use only, not for human use.
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Brief Description5-Methyltryptamine hydrochloride is a high-affinity 5-HT1C receptor ligand and a partial agonist of 5-HT.
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Description5-Methyltryptamine hydrochloride is a high-affinity 5-HT1C receptor ligand and a partial agonist of 5-HT. 5-Methyltryptamine hydrochloride protects mice subjected to burn, tourniquet and endotoxin shock.(In Vitro):5-Methyltryptamine stimulates breakdown of endogenous [3H]inositol-labeled phosphoinositides in membranes prepared from blowfly salivary gland homogenates. 5-Methyltryptamine, in the presence of 10 microM GTP gamma S, increased the rate of inositol trisphosphate formation by approximately 500% within 30 s.(In Vivo):5-Methyltryptamine contracts trachea with lower potency (-log EC50 < 5) than 5-HT (-log EC50 = 6.98). Guinea pig tracheal contraction to 5-HT and 5-Methyltryptamine is inhibited by 1-(1-naphthyl)piperazine (1-NP, 30 nM).
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Synonyms2-(5-Methyl-1H-indol-3-yl)ethanamine hydrochloride
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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RecptorCleavable
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Research Area——
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Indication——
Chemical Information
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CAS Number1010-95-3
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Formula Weight210.7
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Molecular FormulaC11H15ClN2
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Purity>98% (HPLC)
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Solubility——
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SMILESCl.Cc1ccc2[nH]cc(CCN)c2c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Bak A, et al. Synthesis and evaluation of the physicochemical properties of esterase-sensitive cyclic prodrugs of opioid peptides using an (acyloxy)alkoxy linker. J Pept Res. 1999 Apr;53(4):393-402.
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