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5-Methyltryptamine hydrochloride

CAS No. 1010-95-3

5-Methyltryptamine hydrochloride ( 2-(5-Methyl-1H-indol-3-yl)ethanamine hydrochloride )

Catalog No. M27167 CAS No. 1010-95-3

5-Methyltryptamine hydrochloride is a high-affinity 5-HT1C receptor ligand and a partial agonist of 5-HT.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    5-Methyltryptamine hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    5-Methyltryptamine hydrochloride is a high-affinity 5-HT1C receptor ligand and a partial agonist of 5-HT.
  • Description
    5-Methyltryptamine hydrochloride is a high-affinity 5-HT1C receptor ligand and a partial agonist of 5-HT. 5-Methyltryptamine hydrochloride protects mice subjected to burn, tourniquet and endotoxin shock.(In Vitro):5-Methyltryptamine stimulates breakdown of endogenous [3H]inositol-labeled phosphoinositides in membranes prepared from blowfly salivary gland homogenates. 5-Methyltryptamine, in the presence of 10 microM GTP gamma S, increased the rate of inositol trisphosphate formation by approximately 500% within 30 s.(In Vivo):5-Methyltryptamine contracts trachea with lower potency (-log EC50 < 5) than 5-HT (-log EC50 = 6.98). Guinea pig tracheal contraction to 5-HT and 5-Methyltryptamine is inhibited by 1-(1-naphthyl)piperazine (1-NP, 30 nM).
  • Synonyms
    2-(5-Methyl-1H-indol-3-yl)ethanamine hydrochloride
  • Pathway
    Endocrinology/Hormones
  • Target
    5-HT Receptor
  • Recptor
    Cleavable
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1010-95-3
  • Formula Weight
    210.7
  • Molecular Formula
    C11H15ClN2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.Cc1ccc2[nH]cc(CCN)c2c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Bak A, et al. Synthesis and evaluation of the physicochemical properties of esterase-sensitive cyclic prodrugs of opioid peptides using an (acyloxy)alkoxy linker. J Pept Res. 1999 Apr;53(4):393-402.
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